Modified colorimetric method for procainamide in plasma.

نویسندگان

  • D S Sitar
  • D N Graham
  • R E Rangno
  • L R Dusfresne
  • R I Ogilvie
چکیده

We describe a modified colorimetric method for determining procainamide in plasma by use of a diazotization and coupling reaction with N-(1-naphthyl)-ethylenediamine dihydrochloride (Marshall's reagent). The sensitivity of the assay is increased twofold over the originally reported colorimetric method, and the lower limit of detection for the assay of a 1.0-ml plasma sample has been decreased to 0.5 mg/liter.

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عنوان ژورنال:
  • Clinical chemistry

دوره 22 3  شماره 

صفحات  -

تاریخ انتشار 1976